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CHICAGO (BUSINESS WIRE) Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced the first presentation of data evaluating pembrolizumab (MK 3475), Merck's investigational anti PD 1 antibody, as initial therapy in patients with PD L1 positive, advanced non small cell Crossbody Louis Vuitton Purse lung cancer (NSCLC). In previously untreated patients, the objective response rate (ORR) (confirmed and unconfirmed) with pembrolizumab as a single agent (monotherapy) was 47 percent by investigator assessed, immune related response criteria (irRC) (n=21/45: 95% CI, 32 62) and 26 percent by centrally evaluated RECIST v1.1 (Response Evaluation Criteria in Solid Tumors) (n=11/42: 95% CI, 14 42). In evaluable patients who had measurable disease with one post baseline scan, 80 percent demonstrated tumor shrinkage as measured by centrally evaluated RECIST criteria (n=28/35). The median duration of response has not been reached, with some patients continuing on treatment with pembrolizumab as monotherapy for at least one year.

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